Rome is the capital city and a special comune of Italy (named Comune di Roma Capitale). Rome also serves as the capital of the Lazio region. With 2,872,800 residents in 1,285 km2(496.1 sq mi), it is also the country's most populated comune. It is the fourth-most populous city in the European Union by population within city limits. It is the centre of the Metropolitan City of Rome, which has a population of 4,355,725 residents, thus making it the most populous metropolitan city in Italy. Rome is located in the central-western portion of the Italian Peninsula, within Lazio (Latium), along the shores of the Tiber. The Vatican City (the smallest country in the world) is an independent country inside the city boundaries of Rome, the only existing example of a country within a city: for this reason Rome has been often defined as capital of two states.

Rome's history spans 28 centuries. While Roman mythology dates the founding of Rome at around 753 BC, the site has been inhabited for much longer, making it one of the oldest continuously occupied sites in Europe. The city's early population originated from a mix of Latins, Etruscans, and Sabines. Eventually, the city successively became the capital of the Roman Kingdom, the Roman Republic and the Roman Empire, and is regarded as the birthplace of Western civilization and by some as the first ever metropolis. It was first called The Eternal City (Latin: Urbs Aeterna; Italian: La Città Eterna) by the Roman poet Tibullus in the 1st century BC, and the expression was also taken up by Ovid, Virgil, and Livy. Rome is also called the "Caput Mundi" (Capital of the World). After the fall of the Western Empire, which marked the beginning of the Middle Ages, Rome slowly fell under the political control of the Papacy, which had settled in the city since the 1st century AD, until in the 8th century it became the capital of the Papal States, which lasted until 1870. Beginning with the Renaissance, almost all the popes since Nicholas V (1447–1455) pursued over four hundred years a coherent architectural and urban programme aimed at making the city the artistic and cultural centre of the world. In this way, Rome became first one of the major centres of the Italian Renaissance, and then the birthplace of both the Baroque style and Neoclassicism. Famous artists, painters, sculptors and architects made Rome the centre of their activity, creating masterpieces throughout the city. In 1871, Rome became the capital of the Kingdom of Italy, which, in 1946, became the Italian Republic.

Rome has the status of a global city. In 2016, Rome ranked as the 14th-most-visited city in the world, 3rd most visited in the European Union, and the most popular tourist attraction in Italy. Its historic centre is listed by UNESCO as a World Heritage Site. The famous Vatican Museums are among the world's most visited museums while the Colosseum was the most popular tourist attraction in world with 7.4 million visitors in 2018. Host city for the 1960 Summer Olympics, Rome is the seat of several specialized agencies of the United Nations, such as the Food and Agriculture Organization (FAO), the World Food Programme (WFP) and the International Fund for Agricultural Development (IFAD). The city also hosts the Secretariat of the Parliamentary Assembly of the Union for the Mediterranean (UfM) as well as the headquarters of many international business companies such as Eni, Enel, TIM, Leonardo S.p.A., and national and international banks such as Unicredit and BNL. Its business district, called EUR, is the base of many companies involved in the oil industry, the pharmaceutical industry, and financial services. Rome is also an important fashion and design centre thanks to renowned international brands centered in the city. Rome's Cinecittà Studios have been the set of many Academy Award–winning movies.

Salerno is one of the most popular seaside cities in Italy, intended for recreation at sea. The climate here is warm and mild, which is typical for all cities of the Neapolitan Riviera. Tourism in Salerno is at a high level, as the city is a rich historical and cultural center. Salerno contains many attractions interesting for lovers of history, art and culture.

The capital of Malta - Valletta , is the first and almost the only city in Europe, which was once designed by architects and built according to all the rules and norms of construction. Valletta is considered to be one of the most beautiful cities on the Mediterranean. Klaipeda is on the list of the few remaining fortified towns. The center of the city is the Palace of the Grand Master of the Order of Malta, and today the residence of the President of the country, here is the seat of the Maltese Parliament. The list of places to visit in Valletta includes the Castilla Palace, the Admiralty (where the National Museum of Fine Arts is now located, with the largest painting collection in the country), a charming place in the city - the beautiful Hastings Gardens, and this is not the whole list of the riches of the capital of Malta .

Through the scents of olive groves and the salty breeze of the Adriatic, travelers are welcomed by Bar, a coastal town in Montenegro that blends ancient history with seaside charm. Here, you can wander the streets of Stari Bar, where ruins of old fortresses echo Ottoman and Venetian influences, or taste local wine in the shade of a centuries-old olive tree — one of the oldest in Europe.

Modern Bar also offers comfortable beaches, fresh seafood, and excellent opportunities for yachting. It’s a perfect destination for those seeking not just sea and sun, but also a touch of authentic Balkan culture. Thanks to a convenient ferry connection with Italy, Bar is also a great starting point for Adriatic adventures.

Kotor is a coastal town in Montenegro. It is located in a secluded part of the Gulf of Kotor. The city has a population of 13,510 and is the administrative center of Kotor Municipality.

The old Mediterranean port of Kotor is surrounded by fortifications built during the Venetian period. It is located on the Bay of Kotor (Boka Kotorska), one of the most indented parts of the Adriatic Sea. Some have called it the southern-most fjord in Europe, but it is a ria, a submerged river canyon. Together with the nearly overhanging limestone cliffs of Orjen and Lovćen, Kotor and its surrounding area form an impressive landscape.

Since the early 2000s Kotor has seen an increase in tourists , many of them coming by cruise ship. Visitors are attracted by the natural environment of the Gulf of Kotor and by the old town of Kotor. Kotor is part of the World Heritage Site dubbed the Natural and Culturo-Historical Region of Kotor.

The fortified city of Kotor was also included in UNESCO's World Heritage Site list as part of Venetian Works of Defence between 15th and 17th centuries: Stato da Terra – western Stato da Mar in 201

Dubrovnik is a Croatian city on the Adriatic Sea. It is one of the most prominent tourist destinations in the Mediterranean Sea, a seaport and the centre of Dubrovnik-Neretva County. Its total population is 42,615 (census 2011). In 1979, the city of Dubrovnik joined the UNESCO list of World Heritage sites.

The prosperity of the city was historically based on maritime trade; as the capital of the maritime Republic of Ragusa, it achieved a high level of development, particularly during the 15th and 16th centuries, as it became notable for its wealth and skilled diplomacy.

In 1991, after the break-up of Yugoslavia, Dubrovnik was besieged by Serbian and Montenegrin soldiers of the Yugoslav People's Army (JNA) for seven months and suffered significant damage from shelling. After repair and restoration works in the 1990s and early 2000s, Dubrovnik re-emerged as one of the top tourist destinations in the Mediterranean.