Monte Carlo officially refers to an administrative area of the Principality of Monaco, specifically the ward of Monte Carlo/Spélugues, where the Monte Carlo Casino is located. Informally the name also refers to a larger district, the Monte Carlo Quarter (corresponding to the former municipality of Monte Carlo), which besides Monte Carlo/Spélugues also includes the wards of La Rousse/Saint Roman, Larvotto/Bas Moulins, and Saint Michel. The permanent population of the ward of Monte Carlo is about 3,500, while that of the quarter is about 15,000. Monaco has four traditional quarters. From west to east they are: Fontvieille (the newest), Monaco-Ville (the oldest), La Condamine, and Monte Carlo.

Monte Carlo (literally "Mount Charles") is situated on a prominent escarpment at the base of the Maritime Alpsalong the French Riviera. Near the quarter's western end is the world-famous Place du Casino, the gamblingcenter which has made Monte Carlo "an international byword for the extravagant display and reckless dispersal of wealth". It is also the location of the Hôtel de Paris, the Café de Paris, and the Salle Garnier (the casino theatre which is the home of the Opéra de Monte-Carlo).

The quarter's eastern part includes the community of Larvotto with Monaco's only public beach, as well as its new convention center (the Grimaldi Forum), and the Monte-Carlo Bay Hotel & Resort. At the quarter's eastern border, one crosses into the French town of Beausoleil (sometimes referred to as Monte-Carlo-Supérieur), and just 8 kilometres (5 mi) to its east is the western border of Italy.

Rome is the capital city and a special comune of Italy (named Comune di Roma Capitale). Rome also serves as the capital of the Lazio region. With 2,872,800 residents in 1,285 km2(496.1 sq mi), it is also the country's most populated comune. It is the fourth-most populous city in the European Union by population within city limits. It is the centre of the Metropolitan City of Rome, which has a population of 4,355,725 residents, thus making it the most populous metropolitan city in Italy. Rome is located in the central-western portion of the Italian Peninsula, within Lazio (Latium), along the shores of the Tiber. The Vatican City (the smallest country in the world) is an independent country inside the city boundaries of Rome, the only existing example of a country within a city: for this reason Rome has been often defined as capital of two states.

Rome's history spans 28 centuries. While Roman mythology dates the founding of Rome at around 753 BC, the site has been inhabited for much longer, making it one of the oldest continuously occupied sites in Europe. The city's early population originated from a mix of Latins, Etruscans, and Sabines. Eventually, the city successively became the capital of the Roman Kingdom, the Roman Republic and the Roman Empire, and is regarded as the birthplace of Western civilization and by some as the first ever metropolis. It was first called The Eternal City (Latin: Urbs Aeterna; Italian: La Città Eterna) by the Roman poet Tibullus in the 1st century BC, and the expression was also taken up by Ovid, Virgil, and Livy. Rome is also called the "Caput Mundi" (Capital of the World). After the fall of the Western Empire, which marked the beginning of the Middle Ages, Rome slowly fell under the political control of the Papacy, which had settled in the city since the 1st century AD, until in the 8th century it became the capital of the Papal States, which lasted until 1870. Beginning with the Renaissance, almost all the popes since Nicholas V (1447–1455) pursued over four hundred years a coherent architectural and urban programme aimed at making the city the artistic and cultural centre of the world. In this way, Rome became first one of the major centres of the Italian Renaissance, and then the birthplace of both the Baroque style and Neoclassicism. Famous artists, painters, sculptors and architects made Rome the centre of their activity, creating masterpieces throughout the city. In 1871, Rome became the capital of the Kingdom of Italy, which, in 1946, became the Italian Republic.

Rome has the status of a global city. In 2016, Rome ranked as the 14th-most-visited city in the world, 3rd most visited in the European Union, and the most popular tourist attraction in Italy. Its historic centre is listed by UNESCO as a World Heritage Site. The famous Vatican Museums are among the world's most visited museums while the Colosseum was the most popular tourist attraction in world with 7.4 million visitors in 2018. Host city for the 1960 Summer Olympics, Rome is the seat of several specialized agencies of the United Nations, such as the Food and Agriculture Organization (FAO), the World Food Programme (WFP) and the International Fund for Agricultural Development (IFAD). The city also hosts the Secretariat of the Parliamentary Assembly of the Union for the Mediterranean (UfM) as well as the headquarters of many international business companies such as Eni, Enel, TIM, Leonardo S.p.A., and national and international banks such as Unicredit and BNL. Its business district, called EUR, is the base of many companies involved in the oil industry, the pharmaceutical industry, and financial services. Rome is also an important fashion and design centre thanks to renowned international brands centered in the city. Rome's Cinecittà Studios have been the set of many Academy Award–winning movies.

Sicily is the largest island in the Mediterranean Sea and one of the 20 regions of Italy. It is one of the five Italian autonomous regions, in Southern Italy along with surrounding minor islands, officially referred to as Regione Siciliana.

Sicily is located in the central Mediterranean Sea, south of the Italian Peninsula, from which it is separated by the narrow Strait of Messina. Its most prominent landmark is Mount Etna, the tallest active volcano in Europe, and one of the most active in the world, currently 3,329 m (10,922 ft) high. The island has a typical Mediterranean climate.

The earliest archaeological evidence of human activity on the island dates from as early as 12,000 BC. By around 750 BC, Sicily had three Phoenician and a dozen Greek colonies and, for the next 600 years, it was the site of the Sicilian Wars and the Punic Wars. After the fall of the Roman Empire in the 5th century AD, Sicily was ruled during the Early Middle Ages by the Vandals, the Ostrogoths, the Byzantine Empire, and the Emirate of Sicily. The Norman conquest of southern Italy led to the creation of the Kingdom of Sicily, which was subsequently ruled by the Hohenstaufen, the Capetian House of Anjou, Spain, and the House of Habsburg. It was finally unified under the House of Bourbon with the Kingdom of Naples as the Kingdom of the Two Sicilies. It became part of Italy in 1860 following the Expedition of the Thousand, a revolt led by Giuseppe Garibaldi during the Italian unification, and a plebiscite. Sicily was given special status as an autonomous region on 15th May 1946, 18 days before the Italian constitutional referendum of 1946. Albeit, much of the autonomy still remains unapplied, especially financial autonomy, because the autonomy-activating laws have been deferred to be approved by the parithetic committee (50% Italian State, 50% Regione Siciliana), since 1946.

Sicily has a rich and unique culture, especially with regard to the arts, music, literature, cuisine, and architecture. It is also home to important archaeological and ancient sites, such as the Necropolis of Pantalica, the Valley of the Temples, Erice and Selinunte.

Corfu or Kerkyra is a Greek island in the Ionian Sea. It is the second largest of the Ionian Islands, and, including its small satellite islands, forms the northwesternmost part of Greece. The island is part of the Corfu regional unit, and is administered as a single municipality, which also includes the smaller islands of Ereikoussa, Mathraki and Othonoi. The municipality has an area of 610,9 km2, the island proper 592,8 km2. The principal city of the island and seat of the municipality (pop. 32,095) is also named Corfu. Corfu is home to the Ionian University.

The island is bound up with the history of Greece from the beginnings of Greek mythology. Its history is full of battles and conquests. Ancient Korkyra took part in the Battle of Sybota which was a catalyst for the Peloponnesian War, and, according to Thucydides, the largest naval battle between Greek city states until that time. Thucydides also reports that Korkyra was one of the three great naval powers of fifth century BC Greece, along with Athens and Corinth. Medieval castles punctuating strategic locations across the island are a legacy of struggles in the Middle Ages against invasions by pirates and the Ottomans. Two of these castles enclose its capital, which is the only city in Greece to be surrounded in such a way. As a result, Corfu's capital has been officially declared a Kastropolis ("castle city") by the Greek government. From medieval times and into the 17th century, the island, having successfully repulsed the Ottomans during several sieges, was recognised as a bulwark of the European States against the Ottoman Empireand became one of the most fortified places in Europe. The fortifications of the island were used by the Venetians to defend against Ottoman intrusion into the Adriatic. Corfu eventually fell under British rule following the Napoleonic Wars. Corfu was eventually ceded by the British Empire along with the remaining islands of the United States of the Ionian Islands, and unification with modern Greece was concluded in 1864 under the Treaty of London.

In 2007, the city's old quarter was added to the UNESCO World Heritage List, following a recommendation by ICOMOS.

Corfu is a very popular tourist destination. The island was the location of the 1994 European Union summit.

Kotor is a coastal town in Montenegro. It is located in a secluded part of the Gulf of Kotor. The city has a population of 13,510 and is the administrative center of Kotor Municipality.

The old Mediterranean port of Kotor is surrounded by fortifications built during the Venetian period. It is located on the Bay of Kotor (Boka Kotorska), one of the most indented parts of the Adriatic Sea. Some have called it the southern-most fjord in Europe, but it is a ria, a submerged river canyon. Together with the nearly overhanging limestone cliffs of Orjen and Lovćen, Kotor and its surrounding area form an impressive landscape.

Since the early 2000s Kotor has seen an increase in tourists , many of them coming by cruise ship. Visitors are attracted by the natural environment of the Gulf of Kotor and by the old town of Kotor. Kotor is part of the World Heritage Site dubbed the Natural and Culturo-Historical Region of Kotor.

The fortified city of Kotor was also included in UNESCO's World Heritage Site list as part of Venetian Works of Defence between 15th and 17th centuries: Stato da Terra – western Stato da Mar in 201

Dubrovnik is a Croatian city on the Adriatic Sea. It is one of the most prominent tourist destinations in the Mediterranean Sea, a seaport and the centre of Dubrovnik-Neretva County. Its total population is 42,615 (census 2011). In 1979, the city of Dubrovnik joined the UNESCO list of World Heritage sites.

The prosperity of the city was historically based on maritime trade; as the capital of the maritime Republic of Ragusa, it achieved a high level of development, particularly during the 15th and 16th centuries, as it became notable for its wealth and skilled diplomacy.

In 1991, after the break-up of Yugoslavia, Dubrovnik was besieged by Serbian and Montenegrin soldiers of the Yugoslav People's Army (JNA) for seven months and suffered significant damage from shelling. After repair and restoration works in the 1990s and early 2000s, Dubrovnik re-emerged as one of the top tourist destinations in the Mediterranean.

Koper is the fifth largest city in Slovenia. Located in the southwestern part of the country, approximately five kilometres (3.1 miles) south of the border with Italy and 20 kilometers (12 miles) from Trieste, Koper is the largest coastal city in the country. It is bordered by the satellite towns of Izola and Ankaran, and anchors the Istrian region. With a unique ecology and biodiversity, it is considered an important national natural resource. It is the oldest recorded urban settlement in Slovenia. The city's Port of Koper is the major contributor to the economy of the eponymous city municipality. With only one percent of Slovenia having a coastline, the influence that the Port of Koper also has on tourism was a factor in Ankaran deciding to leave the municipality in a referendum in 2011 to establish its own. The city is a destination on a number of Mediterranean cruising lines. In 2016, the city expects 65 cruise ship arrivals (for example: Norwegian Spirit, MSC Magnifica, Norwegian Jade, MS Rhapsody of the Seas...) with the season spanning from March to December. Koper is the main urban centre of the Slovenian Istria, with a population of about 25,000.